2-Aminophenol-4-Sulfonanilide

• Category :

  Dyestuffs and Pigments

• Synonyms :

  Benzenesulfonamide, 3-amino-4-hydroxy-N-phenyl-;3-Amino-4-hydroxybenzenesulfonanilide;4-Hydroxymetanilanilide;AI3-62996;NSC 315543;3-Amino-4-hydroxy-N-phenylbenzenesulphonamide;Metanilanilide, 4-hydroxy- (8CI);3-amino-4-hydroxy-N-phenylbenzenesulfonamide;3-amino-4-hydroxybenzenesulfonamide;

• CAS NO :

  80-20-6

• EC NO :

  201-258-9

• Molecular Formula :

  C₆H₈N₂O₃S

• Molecular Weight :

  188.2043

• Main Specifications :

  99% min

• InChI :

  InChI=1/C6H8N2O3S/c7-5-3-4(12(8,10)11)1-2-6(5)9/h1-3,9H,7H2,(H2,8,10,11)

• Packing :

  25kg 50kg drum or bag

• Product description :

  What is the chemical of 2-Aminophenol-4-Sulfonanilide ? Appearance: White to off-white crystalline powder； Assay:99%min by HPLC； IR Identity: conform to standard； HNMR： conform to standard； carbon spectrum: conform to standard； Water by K. F.:0.5% max or as per the customer’s request； Loss on drying:0.5% max. or as per the customer’s request； ============================================================================= 2-Aminophenol-4-sulfonanilide is an important organic synthesis intermediate, mainly used for: Pharmaceutical intermediates: for synthesizing sulfonamide drugs and other active molecules containing a benzene sulfonamide structure. Dye intermediates: as a raw material for preparing certain acidic dyes. Chemical research: used as a structural building block in the development of organic synthesis methodology and drug chemistry research. =============================================================================== Synthesis Route: 2-Aminophenol-4-sulfonanilide is typically synthesized using benzenesulfonyl chloride and o-aminophenol as starting materials through a nucleophilic substitution reaction. The main route is as follows: Sulfonation Reaction: o-Aminophenol (2-aminophenol) reacts with benzenesulfonyl chloride (benzenesulfonyl chloride) under alkaline conditions to generate the target product, 2-aminophenol-4-sulfonanilide. Temperature and pH need to be controlled during the reaction to avoid side reactions. The reaction equation can be simplified as: 2-H?N-C?H?-OH + Cl-SO?-C?H? → 2-H?N-C?H?-O-SO?-C?H? + HCl Post-treatment: After the reaction is complete, the product is purified through acidification, filtration, washing, and recrystallization steps to obtain high-purity crystalline solid (for reference only).

• Uses :

  2-Aminophenol-4-Sulfonanilide是重要的有機(jī)合成中間體

• Molecular Structure :