2-Aminophenol-4-Sulfonanilide
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- Category :
Dyestuffs and Pigments
- CAS NO : 80-20-6
- EC NO : 201-258-9
- Molecular Formula : C6H8N2O3S
- Main Specifications : 99% min
- Synonyms : Benzenesulfonamide, 3-amino-4-hydroxy-N-phenyl-;3-Amino-4-hydroxybenzenesulfonanilide;4-Hydroxymetanilanilide;AI3-62996;NSC 315543;3-Amino-4-hydroxy-N-phenylbenzenesulphonamide;Metanilanilide, 4-hydroxy- (8CI);3-amino-4-hydroxy-N-phenylbenzenesulfonamide;3-amino-4-hydroxybenzenesulfonamide;
Package: 25kg 50kg drum or bag
Uses : 2-Aminophenol-4-Sulfonanilide是重要的有機合成中間體
Molecular Structure:
Product description:
What is the chemical of 2-Aminophenol-4-Sulfonanilide ?
Appearance: White to off-white crystalline powder；
Assay:99%min by HPLC；
IR Identity: conform to standard；
HNMR： conform to standard；
carbon spectrum: conform to standard；
Water by K. F.:0.5% max or as per the customer’s request；
Loss on drying:0.5% max. or as per the customer’s request；
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2-Aminophenol-4-sulfonanilide is an important organic synthesis intermediate, mainly used for: Pharmaceutical intermediates: for synthesizing sulfonamide drugs and other active molecules containing a benzene sulfonamide structure. Dye intermediates: as a raw material for preparing certain acidic dyes. Chemical research: used as a structural building block in the development of organic synthesis methodology and drug chemistry research.
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Synthesis Route:
2-Aminophenol-4-sulfonanilide is typically synthesized using benzenesulfonyl chloride and o-aminophenol as starting materials through a nucleophilic substitution reaction. The main route is as follows:
Sulfonation Reaction: o-Aminophenol (2-aminophenol) reacts with benzenesulfonyl chloride (benzenesulfonyl chloride) under alkaline conditions to generate the target product, 2-aminophenol-4-sulfonanilide. Temperature and pH need to be controlled during the reaction to avoid side reactions.
The reaction equation can be simplified as:
2-H?N-C?H?-OH + Cl-SO?-C?H? → 2-H?N-C?H?-O-SO?-C?H? + HCl
Post-treatment: After the reaction is complete, the product is purified through acidification, filtration, washing, and recrystallization steps to obtain high-purity crystalline solid (for reference only).
If you are sourcing 2-Aminophenol-4-Sulfonanilide from China ,just feel free to inquire
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